| # | Spieler | Team | GP | TOT | SACK | INT | FF |
|---|---|---|---|---|---|---|---|
| 1 | EJ Ernest Jones IV | Seahawks | 15 | 126 | 0.5 | — | — |
| 2 | DT Drake Thomas | Seahawks | 17 | 96 | 3.5 | — | — |
| 3 | TK Tyrice Knight | Seahawks | 16 | 57 | 2.0 | — | — |
| 4 | DL DeMarcus Lawrence | Seahawks | 16 | 53 | 6.0 | — | — |
| 5 | UN Uchenna Nwosu | Seahawks | 16 | 35 | 7.0 | — | — |
| 6 | DH Derick Hall | Seahawks | 14 | 30 | 2.0 | — | — |
| 7 | PO Patrick O'Connell | Seahawks | 9 | 19 | 1.0 | — | — |
| 8 | DF Dante Fowler Jr. | Seahawks | 17 | 15 | 3.0 | — | — |
| 9 | CS Chazz Surratt | Seahawks | 11 | 11 | 0.0 | — | — |
| 10 | CO Connor O'Toole | Seahawks | 8 | 5 | 0.0 | — | — |
| 11 | JW Ja'Markis Weston | Seahawks | 3 | 2 | 0.0 | — | — |
| 12 | JS Jamie Sheriff | Seahawks | 1 | 1 | 0.0 | — | — |
| 13 | JI Jared Ivey | Seahawks | 2 | — | — | — | — |